A secretive outpost in the Romulan Neutral Zone where the geneticist Dr Jago revealed Dal R'El's engineered origins in the Prodigy episode Masquerade.
Noble Isle is a settlement inside the Neutral Zone, beyond the reach of Federation law, visited in the first-season Prodigy episode Masquerade. The Protostar's crew are brought there by the roguish trader Thadiun Okona after fleeing from Vice Admiral Janeway's USS Dauntless.
Its resident scientist, Dr Jago, offers to tell Dal what species he belongs to. She finds that he is an Augment, made by followers of Arik Soong from the genes of dozens of species, and that his abilities have been held dormant. She fits an implant that awakens them.
Dal's body starts shifting uncontrollably from one species' traits to another. The crew remove the implant as Romulans descend on the isle. Meanwhile the Dauntless arrives at the edge of the Zone and Asencia is revealed as a Vau N'Akat agent.