The informal name for four genetically enhanced humans, Jack, Lauren, Patrick and Sarina, who were confined to an institute and brought to Deep Space Nine to work with Doctor Bashir.
The group consists of four people whose parents had them genetically engineered as children, as Bashir's did, but with damaging side effects. Jack is brilliant and aggressive, Lauren seductive, Patrick childlike, and Sarina silent and withdrawn. All have lived for years in an institute under the care of Doctor Karen Loews.
In Statistical Probabilities, they come to the station in the hope that Bashir can draw them out. Given war briefings to study, they produce projections showing the Federation cannot win and should surrender. When Starfleet rejects this, Jack tries to hand intelligence to the Dominion, and Sarina frees Bashir to stop him.
They return in Chrysalis, slipping out of the institute with Patrick dressed as an admiral, and help Bashir devise the treatment that lets Sarina speak.