A transport ship attacked by the Crystalline Entity in 2368 while the Enterprise was tracking the creature, its crew killed before help could reach it.
The Kallisko is a transport ship that appears in the episode Silicon Avatar. In 2368 the Enterprise is following the Crystalline Entity after it strips the colony on Melona IV of life, with the xenologist Kila Marr aboard to help find it.
While the pursuit is under way the Kallisko reports that it is under attack. By the time the Enterprise arrives the ship is adrift and everyone on board is dead, killed in the same way as the Entity's earlier victims.
The loss confirms that the tracking method devised by Data and Marr works, and it hardens Marr's wish for revenge for her son, who died when the Entity destroyed Omicron Theta.