A bustling Federation starbase that hosts a Starfleet command conference in 2381, where Mariner and Boimler cause chaos in An Embarrassment of Dooplers.
Starbase 25 is a large Federation station with a busy civilian promenade, an aviary, shops, a barber and at least one disreputable bar, policed by its own security force.
It is the setting of the Lower Decks second-season episode An Embarrassment of Dooplers, set in 2381. While the USS Cerritos escorts a Doopler emissary there, the station hosts a command conference with an exclusive party. Mariner and Boimler try to get in, a plan that involves an old contact of Mariner's and ends in a kart chase through the base with station security in pursuit.
Shut out of the party, the two end up at a dive bar instead. The bartender points out where Kirk and Spock once carved their names into the counter after being turned away themselves, and the ensigns add their own.