The Krenim colony where the scientist Annorax lived with his wife, erased from history by his own temporal weapon and the object of his two-century quest.
Kyana Prime is a Krenim colony at the heart of the Voyager two-part story Year of Hell.
Annorax designed a ship able to wipe objects out of the timeline, hoping to restore the Krenim Imperium by removing its enemies. His first calculation was flawed: the Imperium grew stronger, but Kyana Prime vanished, and with it his wife.
For some two hundred years he made incursion after incursion, refusing every result that did not bring the colony back. He keeps a lock of his wife's hair as a reminder. When Janeway rams the weapon ship, it erases itself, and the restored timeline shows Annorax at home on Kyana Prime with his wife.