The body that negotiates trade on behalf of the Karemma, a commercial people of the Gamma Quadrant and members of the Dominion, and which dealt with the Federation through Ferengi intermediaries.
The Karemma are the first Dominion member the Ferengi do business with, supplying tulaberry wine in the Deep Space Nine episode Rules of Acquisition. In The Search their official Ornithar reluctantly gives Sisko the location of a Dominion relay station.
The Commerce Ministry itself comes to the fore in Starship Down. In 2372 it asks Starfleet to send the Defiant to the Gamma Quadrant to settle complaints about the trading arrangement, and the minister Hanok tells Sisko that the Ferengi go-betweens, chiefly Quark, have been loading every deal with invented taxes and fees.
The meeting is cut short when Jem'Hadar ships attack the Karemma for trading with the Federation and the battle moves into a gas giant's atmosphere. Trapped together, Hanok and Quark defuse an unexploded torpedo, and Hanok discovers a taste for risk.