A chemical energy source used in reactors and transports which in very pure form can be made into weapons, carried by the Valerians and suspected of supplying the Cardassians.
Dolamide appears in the Deep Space Nine episode Dramatis Personae. A Valerian freighter asks to dock at the station, and Kira objects strongly: during the occupation the Valerians shipped weapons-grade dolamide to the Cardassians, and she believes they are still doing so.
Sisko will not turn the ship away without proof. The disagreement would normally be routine, but a telepathic matrix brought back from the Gamma Quadrant by a dying Klingon crew is driving the staff to re-enact an ancient power struggle.
Under its influence the dolamide question becomes the pretext for a mutiny, with Kira plotting to remove Sisko and O'Brien defending him. Odo, who is unaffected, purges the influence from the station.