An uncrewed warp-driven probe sent out by Earth in 2067 with greetings and technical knowledge, which came down on a Delta Quadrant planet and led its people to ruin.
Friendship 1 was launched in 2067, four years after Zefram Cochrane's first warp flight, by the United Earth Space Probe Agency. It carried greetings, music and instructions for technology, including antimatter, in the hope of reaching other civilisations.
In the seventh-season Voyager episode Friendship One, Starfleet gives Voyager its first official mission in years: find the probe. The crew traces it to a planet in nuclear winter. The inhabitants had used the probe's information to build antimatter reactors, and a containment failure poisoned their world.
The survivors blame humanity and take an away team hostage. Lieutenant Joseph Carey is killed before Janeway can show that Voyager is able to clear the atmosphere.