Place Star Trek: Enterprise · 2154

Yosemite 3

Research station destroyed by the Xindi weapon's escort

A human research station in the Sol system, destroyed with its crew in 2154 by the Xindi-Reptilian ship escorting the superweapon on its final approach to Earth.

Yosemite 3 is a space station seen briefly in the Enterprise episode Zero Hour, the conclusion of the Xindi arc.
When the Xindi weapon comes out of a subspace vortex near Earth in 2154, the Reptilian warship commanded by Dolim is with it. The station lies in their path, and Dolim has it destroyed without hesitation, killing everyone aboard.
The loss shows how little stood between the weapon and Earth while Enterprise was still in the Expanse. Shran's Kumari arrives soon afterwards and destroys Dolim's ship, while Archer's team boards the weapon itself and sets it to overload.