The Klingon colony where experiments with Augment DNA created a plague that changed many Klingons' appearance.
Qu'Vat is a Klingon colony where scientists, including Antaak, worked under General K'Vagh to give Klingons the strengths of human Augments. The experiment went wrong when a patient also had the Levodian flu, creating a plague that spread through the Empire and altered its victims' features.
In Affliction, Phlox is kidnapped and brought to Qu'Vat to find a cure. In Divergence, Admiral Krell moves to destroy the colony to contain the disease, while Archer races to stop him and Phlox finds a cure that leaves its survivors with human-like features.