The Bajoran colony lying closest to the Cardassian border, from which Kira and Odo are returning when they pursue a Maquis ship in Heart of Stone.
Prophet's Landing is mentioned at the opening of Heart of Stone, set in 2371. Kira and Odo have been there to review the colony's security arrangements, a matter of some concern given its exposed position, and are flying home by runabout.
Odo is sulking because Kira accepted the governor's invitation to dinner without consulting him. Their quarrel is cut short when they detect a Maquis vessel attacking a Lissepian supply ship and chase it into the Badlands, where its pilot lands on a small unstable moon.
In the caves there, Kira appears to become trapped in a growing crystal, and Odo, believing she is about to die, confesses that he loves her. The figure is in fact the Female Changeling, who has staged the episode to discover why Odo remains among the solids.